📰 Western diet’ blamed for growing risk of GI cancers among young adults
A recent peer-reviewed study published in the British Journal of Surgery highlights the increasing rates of gastrointestinal (GI) cancers among young adults, attributing the trend to the American diet and lifestyle. Lead researcher Sara Char, M.D., from the Dana Farber Cancer Institute, points out shared risk factors for early-onset GI cancer, including obesity, sedentary lifestyle, excessive alcohol consumption, and smoking. The study notes a surge in rare cancer diagnoses among millennials and Gen X, with colorectal cancer being the most common type among adults under 50. The adoption of a “Western-pattern diet” and sedentary lifestyle by recent generations is believed to contribute to the rising risk of GI cancers. Experts like Paul Oberstein, M.D., emphasize the impact of diet on colon cancer risk and stress the importance of following screening guidelines and adopting healthy lifestyle habits to reduce the risk of GI cancers.
📰 The key to living longer could be tied to a surprising substance, study suggests
A new study conducted by researchers at Emory University suggests that psilocybin, found in magic mushrooms, may extend lifespan by improving cellular health and survival in aged mice. The study, published in Nature, provides experimental evidence that psilocin, the active metabolite in psilocybin, could be a potent geroprotective agent. Psilocybin has gained attention for its potential in treating various psychiatric and neurodegenerative conditions. The treatment with psilocin was found to reduce oxidative stress levels, prevent DNA damage, and increase longevity in mice. Researchers noted that psilocybin impacts multiple hallmarks of aging, leading to healthier cells and longer lifespan.
Psilocybin has shown promise in providing relief from depression for up to five years and benefits for Parkinson’s patients. The treatment with psilocybin was found to slow down the aging process, resulting in healthier cells and longer life in mice. Co-author Louise Hecker highlighted the need for further studies to determine optimal dosing protocols, age for treatment initiation, potential harms, and mechanisms of action of psilocybin. Additional research is needed to confirm the impact of psilocybin on lifespan and to understand its potential benefits and risks in humans. Experts emphasize the importance of administering psychedelics safely and under professional supervision to mitigate potential risks and ensure positive outcomes.
📰 Coffee enema’ social media trend sparks health concerns among doctors
The article discusses the rising trend of “coffee enemas” on social media, where a coffee-water blend is flushed into the colon through the rectum. This practice is believed to stimulate the liver to detox the body, but there are no scientifically proven health benefits, according to Dr. Ligresti. While some individuals report feeling energized or clear-headed after a coffee enema, experts caution against its use due to documented risks such as burns, infections, and caffeine overdose. Dr. Ligresti emphasizes that the liver and kidneys are the body’s natural detoxification systems, and there are safer methods for treating constipation. Nutritionist Mona Sharma advises against coffee enemas and suggests supporting the body’s natural cleansing abilities through proper nourishment and healthy practices.
📰 New weekly injection for Parkinson’s could replace daily pill for millions, study suggests
A new weekly injectable drug developed by scientists from the University of South Australia could potentially revolutionize Parkinson’s disease treatment for over eight million patients by providing sustained release of key medications. The drug aims to replace the need for daily pills, offering a more convenient and effective therapy option. The injectable gel implant combines FDA-approved biodegradable and pH-sensitive substances to gradually release 90% of levodopa and 81% of carbidopa over a week, reducing the need for multiple daily doses. The researchers, led by Professor Sanjay Garg, have successfully tested the system in lab experiments, demonstrating its safety and effectiveness in maintaining consistent drug levels. The technology has been filed for an Australian patent and shows promise for treating other chronic conditions beyond Parkinson’s disease.
📰 Scientists crack the code on new vaccine for deadly plague bacteria
Israeli researchers have developed a new mRNA-based vaccine that is 100% effective against the deadly bacteria causing pneumonic plague, a severe lung infection. The vaccine was tested on animals infected with the bacteria, with all vaccinated animals surviving while unvaccinated ones died. This breakthrough marks the first time an mRNA vaccine has been shown to protect against bacteria, challenging previous beliefs. The researchers combined different strategies to create a stable immune response against the bacterial proteins. The study’s findings were published in the journal Science Advances, demonstrating the potential for mRNA technologies to rapidly address novel threats like antibiotic-resistant bacteria.
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